3Z and biotx.ai Forge Partnership to Advance ADHD Drug Development Using AI Modelling

REYKJAVIK, Iceland and BERLIN, Aug. 18, 2023 /PRNewswire/ — Reykjavik-based drug discovery company, 3Z, and Germany/US-based causal AI firm, biotx.ai, have joined forces in a strategic partnership aimed at revolutionizing ADHD drug development. By leveraging advanced AI modelling techniques, the collaboration seeks to bridge the gap between animal studies and human clinical trials, enabling a more efficient and accurate translation of promising therapeutics.

3Z, holds expertise in developing genetically engineered models of central nervous system disorders, has successfully identified potential ADHD treatments through its innovative zebrafish screening platform. These lead therapeutics, initially discovered in genetically engineered zebrafish, have undergone rigorous retesting in mammalian models to confirm and extend their therapeutic potential. Notably, these novel ADHD therapeutics are non-stimulants, offering a promising alternative with fewer side effects compared to current treatments and addressing the needs of non-responders.

The partnership between 3Z and biotx.ai aims to establish a robust bridge from animal discovery studies to human clinical trials. By utilizing comprehensive AI-powered human genetics-based modelling, the involvement of the lead therapeutic targets in ADHD will be thoroughly explored. This study will provide insights into the targets’ effects on the disorder, predict potential effects on other diseases or disorders, and assess metabolic changes. Real-world zebrafish measurements will be compared to validate the predictions, ultimately simulating a Phase II clinical trial.

The outcome of this groundbreaking AI study will provide a prediction value for the trial’s success or failure, effectively de-risking the lead compound as it enters a real-world clinical trial. By employing AI modelling, the partnership aims to accelerate the drug development process and improve the efficiency of translating findings from animal models to human trials.

Dr. Karl Karlsson, CEO of 3Z and an expert in behavioral neuroscience and biomedical engineering, emphasized the significance of this partnership, stating, “We are entering a new era in drug discovery and development, where AI has the potential to revolutionize the industry. The animal models we develop focus on disorders and diseases that manifest as dysregulation within neuronal networks, which is probably the most challenging aspect to simulate successfully. However, we can model the effects of the drugs we identify on specific genetic targets, enabling us to obtain critical information and significantly reduce the risk of failure going forward.”

For more information about 3Z and biotx.ai, please visit their respective websites at: http://www.3z.is) and http://www.biotx.ai, or follow them on LinkedIn.

About 3Z:

3Z is a Reykjavik-based drug discovery company specializing in genetically engineered models of human central nervous system disorders. Their innovative zebrafish screening platform enables the identification and validation of potential therapeutics for a range of neurological conditions.

About biotx.ai:

biotx.ai developed a causal AI mimicking clinical trials in human genetic data. Internally this has led to 2 drugs, each with high probability of success, now in clinical development. Now biotx.ai makes the same technology  available to biotech and Pharmas.

For media inquiries please contact: 

Dr. Karl Æ. Karlsson  
Email: [email protected]  
Tel: +354-8256467

Subscribe on LinkedIn

Get the free newsletter

Subscribe to MedicaEx for top news, trends & analysis

We're committed to your privacy. MedicaEx uses the information you provide to us to contact you about our relevant content, products, and services. You may unsubscribe from these communications at any time. For more information, check out our Privacy Policy.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

PR Newswire is solely responsible for the content of the above news submissions. If there are any violations of laws, violations of the membership terms of this website, or the risk of infringing on the rights of third parties, PR Newswire will be solely responsible for legal and damage compensation. Responsibility has nothing to do with MedicaEx.

Are you in?

Subscribe to receive exclusive content and notifications to your inbox

We're committed to your privacy. MedicaEx uses the information you provide to us to contact you about our relevant content, products, and services. You may unsubscribe from these communications at any time. For more information, check out our Privacy Policy.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.